TESTA RAYMOND (Total 171 Patents Found)

A novel antibiotic complex exhibiting antifungal activity is produced by fermenting a novel species of bacteria from the genus Aeromonas, the bacterium being herein designated Aeromonas sp. W-10. The antibiotic complex is comprised of at least three and possibly as many as six components and has been designated Antibio...
A novel actinomycete herein designated Micromonospora rhodorangea elaborates a product having substantial antibacterial activity, said activity being due primarily to a novel antibiotic herein designated Antibiotic G-418. The disclosure sets forth methods for producing, isolating and using said antibiotic....
Micromonospora inyoensis strain 1550F-1G NRRL 5742 is incapable of producing antibiotics unless an aminocyclitol is added to the fermentation medium. When such a compound is added, mutamicins are produced, said mutamicins being analogs of known aminoglycoside antibiotics differing therefrom with respect to the aminocyc...
A novel actinomycete herein designated Micromonospora rhodorangea elaborates a product having substantial antibacterial activity, said activity being due primarily to a novel antibiotic herein designated Antibiotic G-418. The disclosure sets forth methods for producing, isolating and using said antibiotic....
This disclosure describes four new antibacterial agents designated LL-CO8078α 1 , LL-CO8078α 2 , LL-CO8078α 3 and LL-CO8078β produced in a microbiological fermentation under controlled conditions using a new strain of a new species of the genus Streptomyces called Streptomyces majorciensis Labeda, sp. nov., and mu...
This invention relates to new polypeptide antibiotics designated LL-BO2964α, LL-BO2964β, LL-BO2964γ, and a mixture thereof designated LL-BO2964, produced during microbiological fermentation, under controlled conditions, using a new strain of Streptomyces coeruleorubidus subspecies rubidus or a mutant thereof. The ne...
The invention provides a process for the production of compounds of the formula: ##STR1## wherein, R, R 3 , R 4 , X and W are defined in the specification in which a compound of the following formula: ##STR2## is reacted with a nucleophile of the formula WH in an inert atmosphere in the presence of a polar-protic or a ...
A novel antibiotic complex exhibiting antifungal activity is produced by fermenting a novel species of bacteria from the genus Aeromonas, the bacterium being herein designated Aeromonas sp. W-10. The antibiotic complex is comprised of at least three and possibly as many as six components and has been designated Antibio...
LA INVENCION SE REFIERE A LOS ANTIBIOTICOS LL-E 19020 ALFA Y LL-19020 BETA DERIVADOS DEL MICROORGANISMO STREPTOMYCES LYDICUS, SUBESPECIE TANZANIUS NRRL 18036, QUE SON UTILES COMO AGENTES ANTIBACTERIANOS. LOS ANTIBIOTICOS LL-E 19020 ALFA Y LL-E 19020 BETA SON TAMBIEN PROMOTORES DE CRECIMIENTO, AGENTES ANTIPROTOZOARIOS Y...
The invention provides compounds of formula I: <see formula I> wherein X, R and R1 are defined in the specification. These compounds are useful as antibiotic agents....
The invention is a process for the production by fermentation of the antibacterial and antiparasitic agents designated LL-D42067α, to methods for its recovery and concentration from crude solutions and to processes for its purification. The invention includes within its scope the biologically pure culture of the antib...
This invention relates to new polypeptide antibiotics designated LL-BO2964α, LL-BO2964β, LL-BO2964γ, and a mixture thereof designated LL-BO2964, produced during microbiological fermentation, under controlled conditions, using a new strain of Streptomyces coeruleorubidus subspecies rubidus or a mutant thereof. The ne...
Antitumor agents LL-D49194α a , LL-D49194β 1 , LL-D49194p 2 , LL-D49194β 3 , LL-D49194y, LL-D49194δ, LL-D49194ε, LL-D49194ζ, LL-D49194η, LL-D49194ω 1 , LL-D49194ω 2 and LL-D49194ω 3 ....
La présente invention concerne un procédé permettant de traiter des infections de l'os ou de la moelle osseuse, l'infection des articulations ou l'infection des tissus entourant l'articulation, par antibiothérapie à base de tigécycline seule ou associée à rifamycine. Dans un mode de réalisation...
Micromonospora arborensis produces a plurality of antibiotics named herein antibiotic 68-1147 complex, when cultivated under controlled aerobic conditions. Two of the antibiotics, antibiotic 68-1147 I and antibiotic 68-1147 II are described and shown to be effective antibacterial agents, especially against gram positiv...
The invention provides a process for the production of compounds of the formula: ##STR1## wherein R, R 3 , R 4 and W are defined in the specification in which a compound of the following formula: ##STR2## is reacted with a nucleophile of the formula WH in an inert atmosphere in the presence of a polar aprotic solvent....
This invention provides a method for treating chronic respiratory disease, fowl cholera and necrotic enteritis in infected birds, by orally administering thereto a pharmaceutically effective amount of antibiotic LL-E19020α, antibiotic LL-E19020β or a physiologically acceptable salt thereof....
本发明涉及治疗骨或骨髓感染、关节感染或关节周边组织感染的方法,包括单独给予替加环素抗生素或联合利福霉素抗生素。在优选实施方案中,骨或骨髓感染引起骨髓炎。在另一个优选实施方案中,关节感染或关节周边组织感染引起脓毒性...